At Advanced Eyecare we are proud to offer Ortho-K for our patients.
All About Ortho-K
Wouldn’t it be great if you could correct your vision and reduce your dependency on glasses or contact lenses-all without having to have laser vision correction surgery? What if you could accomplish this in your sleep? Many individuals have never heard of this, but at Advanced EyeCare we have many patients of all ages that have made this a reality. It’s called orthokeratology, or Ortho-K.
Here at Advanced Eyecare we are proud to offer Ortho-K for our patients.
Many people seek vision correction solutions outside of glasses and traditional contact lenses and they prefer to avoid surgery if possible. Whether you struggle with dry eye, have contact lens intolerance, or simply wish to get rid of your glasses and wish to improve your vision as dramatically as surgery would, you may be interested in orthokeratology, commonly known as “Ortho-K”.
What is Ortho-K?
Orthokeratology (Ortho-K) is the science of changing the curvature or shape of the cornea by wearing highly ”breathable” contact lenses while you sleep. Upon awakening, you remove the lenses and can see clearly during the day without the aid of glasses or contact lenses.Ortho-K is known by many names such as corneal reshaping therapy (CRT) and Vision Shaping Treatment (VST). At Advanced EyeCare, you can be fit with our custom designed Advanced Ortho-K (AOK) lenses.
At Advanced EyeCare, we prescribe OrthoK for two reasons:
To correct prescriptions including nearsightedness (myopia), farsightedness (hyperopia), and in some cases, it is also used to correct presbyopia (the inability to focus up close usually after the age of 40).
It is also used to slow the progression of childhood myopia. Click here to read more about myopia control.
Who Is a Good Candidate for Ortho-K?
Most people with myopia and hyperopia (with or without mild astigmatism) are good candidates for Ortho-K.
Because the corneal reshaping effect is temporary, little risk is involved, and you can discontinue wearing the lenses at any time — provided you are willing to start wearing glasses or contacts again when your prescription returns!
Children and young adults who want to be glasses-free but are too young for LASIK or are not good candidates for refractive surgery for other reasons (dry eyes, for example) are often good candidates for Ortho-K. People who participate in contact sports or work in dusty environments that can pose problems for contact lens wear also can be good candidates.
(Contact Lens And Myopia Progression)
This study had several goals. To evaluate the effect of rigid lenses on myopia progression in children. To determine the mechanism of effect if one exists. To examine the efficacy of rigid contact lenses for the treatment of myopia in young children. To compare vision and comfort issues between rigid and soft contact lens wearers. The conclusions of this study are as follows: Rigid gas permeable lenses produce a slower rate of progression of myopia in children than soft contact lenses. Although corneal curvature changed, the axial growth was not significantly different between the groups. The decreased refractive error progression is not accompanied by slowed axial growth. The corneal curvature changes during corneal reshaping contact lens wear are reversible. The treatment effect experienced in the CLAMP study may not be permanent. Most of the effect on refractive error was limited to the first year of the trial. The study did not indicate that rigid gas permeable lenses should be prescribed primarily for the intent of myopia control.
This study examined the control of myopia progression comparing rigid gas permeable contact lenses versus spectacles. The results showed that the mean increase in myopia for the gas permeable lens was 0.42 diopters per year versus a mean increase in myopia for the spectacle wearers of 0.78 diopters per year. The mean increase in axial length for the gas permeable lens was 0.22 mm per year versus a mean increase in axial length for the spectacle wearers of 0.31 mm per year. The study showed that the decrease in progression of myopia using gas permeable lenses is attributable to mix of axial length growth reduction and corneal flattening.
(The Longitudinal Ortho-k Research In Children)
This study looked at several factors. It was to determine whether Orthokeratology can effectively reduce and control myopia in children. It also compared Orthokeratology treatment with single vision spectacles. It monitored the growth of axial length and the vitreous chamber depth. It also monitored corneal curvature and the relationships with changes of refractive errors. The conclusions of the study found that the subjects found post Orthokeratology unaided vision acceptable in the daytime. The mean increase in axial length for the Orthokeratology group was 0.14 mm per year compared with the mean increase in axial length for the spectacle lens wearers of 0.27 mm per year. In the spectacle wearing group, the eye elongation is faster in those with higher baseline prescriptions. Orthokeratology would benefit higher baseline prescriptions as eye elongation is slower in these subjects. Higher myopia showed greater slowing of progression in the Orthokeratology group.
(Stabilizing Myopia by Accelerating Reshaping Technique)
This study is to determine if wearing Orthokeratology lenses on an overnight basis stops or slows the progression of myopia in children. The group being studied is eight to eleven years old. This group will be compared to spherical soft lens wearers. This study is currently underway so no data is yet available.
Abstract: The use of Orthokeratology for overnight wear raises many questions of safety, efficacy and the effects of myopia stabilization. Orthokeratology or corneal reshaping produces a temporary reduction of myopia by changing the shape (flattening) of the cornea, which is elastic in nature. Flattening the cornea reduces the focusing power of the eye, and if the amount of corneal flattening is properly controlled, it is possible to bring the eye into correct focus and compensate for myopia. Upon removal of the contact lens, the cornea retains its altered shape for a period of time. The global prevalence of myopia is increasing significantly in the school age population. It is estimated that one billion of the six billion people in the world are myopic. (3) Not only is the prevalence increasing but the degree of myopia has also increased. The prevalence of myopia in the United States is estimated to be 25%, in India to be 19% and in the Asian nations the rates of myopia are greater than 75%(1,2,3).
Studies have shown that complications from myopia, such as chorioretinal degeneration and retinal detachment will increase with increasing myopia. The application of corneal reshaping or orthokeratology may potentially stabilize the progressive nature of myopia throughout the adolescent years. Additionally, if wearing corneal reshaping lenses controls the progression of myopia, there also may be a reduction in the rates of adverse effects of advancing myopia. The fact that myopia is on the rise indicates that although the wearing of spectacles clears the vision, it does nothing to control the progression of myopia and its adverse effects.
Conclusions: The initial recruitment phase, fitting statistics, and demographics provide the structure for the five year SMART investigation. Initial dispensing data for corneal reshaping test subjects showed a high first lens success rate to achieve 20/20 unaided acuity. Long term results of this study will provide fitting information, myopia progression comparative data, anatomical differences, and subjective responses to each lens modality. 80.5% of the test group were fit able to use the initial empirically fit lens and did not require a lens change.
Contact Lens Spectrum Issue: December 2010
Together, two major developments in the field of eye care may substantially change our profession. The drastic increase in the prevalence of myopia and the knowledge that the peripheral retina plays a dominant role in the development of myopia progression may dramatically change the scope of how we practice. Contact lens myopia control has gained traction and new evidence suggests it has great potential, although many questions remain unanswered for the moment.
Myopia is becoming increasingly prevalent in the United States and throughout the world. Last year researchers reported that the prevalence of myopia in the United States increased from 25 percent in 1971 to 1972 to 41.6 percent in 1999 to 2004. The survey, using similar protocols in each time period, was based on data from 4,436 Americans in 1971 to 1972 and from 8,339 Americans in 1999 to 2004 (Vitale et al, 2009).In Asia the number of myopic children is even more dramatic, exceeding 80 percent in Taiwan (Lin et al, 1999).The second major myopia development comes from the field of contact lenses, more precisely from corneal reshaping with orthokeratology lenses (Figure 1). For decades, practitioners actively fitting this modality reported anecdotal evidence that myopia appears to develop at a much slower rate in children wearing an overnight orthokeratology modality than in children wearing soft lenses or glasses. For years this clinical belief was disregarded because it was thought to be due to corneal change rather than to slowing of axial elongation. Corneal flattening alone would not yield a potentially permanent slowing of myopia progression, but recent work has proven that there is indeed a significant slowing of axial elongation in kids wearing overnight orthokeratology versus other correction methods.
Figure 1. Anecdotal evidence suggests that myopia appears to develop at a much slower rate in children in an overnight orthokeratology modality than in children wearing soft lenses or glasses.The studies, from totally different parts of the world—the United States, Hong Kong, and Australia—all show fairly similar results: a reduction in the progression of myopia (Cho et al, 2005; Swarbrick et al, 2010; Walline et al, 2009). Two investigations compared axial elongation of orthokeratology contact lens wearers to historical control groups of single vision spectacle wearers (Cho et al, 2005) or soft contact lens wearers (Walline et al, 2009). For more than two years, these studies found approximately a 50 percent reduction in axial elongation. Recent data reported by Swarbrick et al (2010) showed slowed eye growth for eyes wearing orthokeratology contact lenses compared to the contralateral eyes wearing alignment fit GP contact lenses.
The big question is: why is this happening? For that we have to take a look at the peripheral retina. In the 1970s, a Dutch army ophthalmologist, Hoogerheide, reported on “relative hyperopia in myopes.” In emmetropic eyes, light focuses at or slightly in front of the entire retina. In corrected myopes, the central image is focused on the retina, but light is focused behind the peripheral retina (Figures 2 and 3).
Figure 2. Myopic correction with a conventional contact lens creates a hyperopic defocus in the periphery that stimulates further increase in axial length.Figure 3. Myopic correction with an orthokeratology lens design creates a myopic defocus in the periphery, which may slow myopic progression.Through emmetropization, the retina moves to where light is focused. The eye grows slower in response to myopic blur and faster in response to hyperopic blur in an attempt to obtain clear vision. Previously, the central retina, or macula, was thought to be responsible for this emmetropization process, but recent animal studies indicate that the peripheral retina is more important for emmetropization than previously believed. Form deprivation (vision through a translucent shell) causes primate eyes to become myopic, even when only the peripheral retina is affected. If the peripheral form deprivation is removed, the eye returns to emmetropia, even if the fovea is ablated and no longer functioning (Smith et al, 2005). The same is true with peripheral hyperopic blur, which leads to myopic eye growth (Smith et al, 2009). This explains why correction of accommodative lag with bifocal spectacles may not be as effective as was theorized. The central blur may not be as strong of a signal to control eye growth as was previously believed.Traditionally, when eyecare practitioners corrected myopia with glasses and contact lenses, they corrected the central refractive error. However, correction of central myopic refractive error results in peripheral hyperopic refractive error, which may act as a signal to increase eye growth until the peripheral retina reaches the peripheral image shell.
Glasses and contact lenses lead to similar amounts of peripheral hyperopia when myopia is corrected. Spherical contact lenses have no effect on axial elongation in children, compared to spectacles (Horner et al, 1999; Walline et al, 2008). GP lenses were found to affect myopia progression, but the majority of the treatment effect was due to corneal flattening, and axial elongation—the affect that is assumed to represent a permanent treatment effect—was not different between GP and soft lens wearers. (Katz et al, 2003; Walline et al, 2004). Soft and GP contact lenses both result in peripheral hyperopic blur, similar to glasses, indicating why they may not slow the progression of myopia.As the peripheral retina seems to be responsible, at least in part, for eye development in children, orthokeratology experts wondered, “Is this the mechanism responsible for the myopia progression reduction in corneal reshaping?” Several clinicians and researchers have reported that the midperipheral corneal steepening in myopic orthokeratology may lead to peripheral myopic blur, which may act as a signal to slow eye growth. Indeed, orthokeratology has been found to create central emmetropia with peripheral myopia (Charman et al, 2006; Queiros et al, 2010).Two non-randomized clinical trials report approximately a 50 percent reduction of axial elongation with orthokeratology contact lens wear, and Swarbrick and colleagues (2010) recently presented data from the first randomized clinical trial at ARVO. Fourteen myopic children (ages 10 to 17 years) of East Asian ethnicity were fitted with orthokeratology lenses in one eye and conventional GP lenses in the other eye. Lenses were worn for a six-month period, and after a two-week washout without lens wear, the lens-eye combination was reversed for six months. Axial length had increased by 0.06 ± 0.09mm in the GP eye (protected post-hoc paired t-test, p=0.014), but showed no significant change (?0.02 ± 0.08 mm) in the ortho-k eye (p=0.348). During the second six-month period, axial length in the GP eye increased by 0.11 ± 0.11 mm (p=0.002), whereas in the ortho-k eye there was no significant change in axial length (?0.02 ± 0.12 mm; p=0.460) (Swarbrick et al, 2010).
Soft bifocal lenses with a distance center may affect peripheral myopia in a way similar to orthokeratology, and they have also shown to effectively slow down myopia progression. Thomas Aller, OD, a California practitioner, published a case report of 12-year-old identical twins who were randomly fit with distance-center bifocal and single vision soft contact lenses (Aller and Wildsoet, 2008). The child wearing the single vision lenses over the first year showed significant myopic progression, increasing ?1.19D (binocular average), while the child wearing the bifocal contact lenses showed no progression (+0.13D). Since then, several groups have described a variety of soft lens designs to correct peripheral hyperopia and potentially slow myopia progression.Nour and colleagues (2010) reported fitting marmosets with soft lenses that have two alternating powers (?5.00D and +5.00D) arranged in concentric zones centered around a ?5.00D central zone and resulting in similar surface area for each power over a 2.8mm pupil (average diameter of marmoset pupils). The study indicated that when retinal defocus of opposite sign is imposed simultaneously on the primate retina, myopic defocus appears to dominate in most, but not all, of the tested eyes. These results suggest that properly balanced multizone contact lenses may be an effective treatment for preventing, or even reversing, the development of myopia (Nour et al, 2010).John Phillips, from the University of Auckland in New Zealand, showed that myopic peripheral retinal defocus with a simultaneous clear central retinal image using a dual-focus soft lens in 40 11- to 14-year-old children slowed childhood myopia progression over a 10-month period (Phillips and Anstice, 2010). These lenses had a central myopia correction zone and a concentric treatment zone with 2.00D of peripheral retinal defocus. The control lens was a single vision distance lens (same lens form but without treatment zones) worn on the fellow eye. Myopia progression and eye elongation were significantly reduced in eyes wearing the dual-focus lenses than in those wearing single vision lenses. The rate of progression was approximately 0.55D for the dual-focus lens compared to approximately 1.00D for the control lens.Finally, a silicone hydrogel lens was designed in Australia to fully correct central vision but reduce relative peripheral hyperopia. A group of 65 children, all between the ages of 7 to 14 years, wore the peripheral hyperopia-correcting lenses while 50 other children wore standard sphero-cylindrical spectacles. After six months of wear, progression of myopia with the contact lens designed to reduce relative peripheral hyperopia was 54 percent less than that with standard sphero-cylindrical spectacles (Holden et al, 2010).
Many questions still need to be answered, and practitioners need to be careful not to be too optimistic regarding potential myopia control treatments. Careful consideration should be made regarding the clinical meaning of the myopia reduction. A 50 percent reduction is meaningful if the control group progresses significantly. If the control group progresses ?3.00D, then a 50 percent treatment effect yields a 1.50D difference between the treatment and the control groups. However, if the control group progresses only ?1.00D, then a 50 percent treatment effect yields a 0.50D difference between the treatment and control groups. Similarly, a statistically significant effect may not be clinically meaningful. The Correction of Myopia Evaluation Trial (COMET) found a statistically significant treatment effect, but the difference between the treatment and control group was only 0.20D after three years, which is not clinically meaningful (Gwiazda et al, 2003).Practitioners should also note whether the initial treatment effect continues to increase or whether the treatment and control groups progress at exactly the same rate after the first year of treatment. Several myopia control studies have exhibited significant treatment effects in the first year that fail to continue thereafter, eventually reducing the treatment effect to one that is much less meaningful than if the two groups had continued to progress at the same rates as the first year of the study (Gwiazda et al, 2003; Chua et al, 2006).Along those same lines, what happens when the child discontinues contact lens wear? Do the eyes increase progression, then stabilize where they would have without myopia control treatment? Do they remain less myopic than they would have been without myopia control treatment? This is a particularly hard issue to investigate from an ethical point of view because if a treatment slows myopia progression, then it is difficult to ask the patients to stop using the treatment.Currently, all myopia control studies are conducted on children, but what about adult-onset myopia? Will the same treatments slow down adult-onset myopia, too? Furthermore, can pharmaceutical agents slow myopia progression, either alone or in addition to optical control of myopia progression? Finally, if we can slow myopia progression, can we prevent the onset of myopia?To begin answering some of these questions, we need to determine the true mechanism of the treatment effect. In other words, how and why does the peripheral retina detect the optical signals that may control axial elongation of the eye? The control of eye growth appears to be local to the retina, as opposed to higher level neurological processing, perhaps in the brain. Chickens with severed optic nerves still respond to stimuli that signal myopic eye growth (Wildsoet and Wallman, 1995), and optical signals to increase eye growth presented to only half of the eye result in a myopic portion of the eye, not an entirely myopic eye (Smith et al, 2009). However, the specific mechanism responsible for detecting the optical signal is still unknown.Despite all of the questions that remain, some answers have been provided. For example, if a contact lens myopia control treatment is developed, we can be certain that children are capable of wearing the treatment. Children have been shown to be capable of wearing and independently caring for soft, GP, and orthokeratology contact lenses (Cho et al, 2005; Walline et al, 2009). Although children are able to independently care for their lenses, they should be reminded of the appropriate care regimen on a regular basis to help them maintain good standards of care and decrease the likelihood that they will experience problems with their lenses.
In the meantime, many contact lens industry partners are attempting to design contact lenses to control myopia progression. Ultimately, eyecare practitioners may advance from “myopia correctors” to “myopia managers.” If all this new information on myopia control is substantiated in the future, children may seek contact lenses for optical correction and myopia control much more frequently than before, so eyecare practitioners should become comfortable fitting contact lenses to a younger population.This is a very exciting time for treating and possibly reducing myopia in children, so read the literature, seek continuing education, and pay attention to the lay press because you don’t want to be caught off guard if and when a new myopia control treatment becomes available.
For references, please visit www.clspectrum.com/references.asp and click on document #181.
How much does Ortho-K cost?
At Advanced EyeCare we use our considerable expertise to custom fit a lens that is specifically tailored to your vision needs. The cost can vary depending on the level of your existing prescription and whether you are choosing ortho-k for prevention of myopia progression. Normally, orthokeratology is not covered completely by vision care insurance plans, but a portion may be billable. The initial cost is usually half of the cost of LASIK and at Advanced EyeCare, a monthly supply starts as low as $50/month.
Please click the links below to listen in on Dr. Ben Larson’s Teleconference on the topic of Ortho- K!